Production of tumour necrosis factor during murine cutaneous leishmaniasis

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Production of tumour necrosis factor during murine cutaneous leishmaniasis.

We have assessed the role of tumour necrosis factor-alpha (TNF) during cutaneous leishmaniasis and demonstrated that significant levels of TNF were released by spleen cells from infected mice after in vitro restimulation with Leishmania major promastigotes. Spleen cells from both genetically resistant and genetically susceptible mice were equally capable of producing TNF. After challenge with b...

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ژورنال

عنوان ژورنال: Parasite Immunology

سال: 1990

ISSN: 0141-9838,1365-3024

DOI: 10.1111/j.1365-3024.1990.tb00983.x